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1- Department of Environmental Health, Faculty of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran.
2- Department of Statistics, School of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran.
3- Department of Neurology, Medical Faculty, Zanjan University of Medical Sciences, Zanjan, Iran.
4- Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
2- Department of Statistics, School of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran.
3- Department of Neurology, Medical Faculty, Zanjan University of Medical Sciences, Zanjan, Iran.
4- Neurosciences Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran.
Abstract: (125 Views)
Background: Rising urban air pollution, including PM10, PM2.5, O3, SO2, NO2, and CO, poses a significant public health threat and may be a risk factor for stroke.
Methods: This study was conducted between 2020 and 2023 at Imam Reza Hospital in Tabriz. Data on stroke patients were collected from the Tabriz Stroke Registry, and daily air pollutant data were obtained from the Environmental Protection Agency website. Descriptive statistical analyses, along with Poisson and negative binomial regression models, were used to assess the association between air pollutant exposure and stroke incidence.
Results: PM2.5 was identified as the primary pollutant during 89.30% of the study period. The mean daily stroke incidence was 1.35 (SD: 1.17), with the highest incidence observed on days dominated by SO2 (1.91, SD: 0.83) and the lowest on days dominated by O3 (1.21, SD: 1.27). SO2 had the highest mean Air Quality Index (AQI) value (mean: 84, SD: 36), whereas O3 showed the lowest (mean: 42, SD: 13). PM2.5 showed a significant positive association with stroke incidence (IRR: 1.003, 95% CI: 1.001-1.005, P < 0.001), corresponding to a 0.3% increase in stroke incidence per unit rise in PM2.5-related AQI. No statistically significant associations were observed for the other air pollutants.
Conclusion: Elevated PM2.5 levels were associated with increased stroke incidence, while other air pollutants showed no significant correlations. These findings underscore the importance of effective management of particulate matter sources and the strengthening of air quality monitoring systems to mitigate stroke risk.
Methods: This study was conducted between 2020 and 2023 at Imam Reza Hospital in Tabriz. Data on stroke patients were collected from the Tabriz Stroke Registry, and daily air pollutant data were obtained from the Environmental Protection Agency website. Descriptive statistical analyses, along with Poisson and negative binomial regression models, were used to assess the association between air pollutant exposure and stroke incidence.
Results: PM2.5 was identified as the primary pollutant during 89.30% of the study period. The mean daily stroke incidence was 1.35 (SD: 1.17), with the highest incidence observed on days dominated by SO2 (1.91, SD: 0.83) and the lowest on days dominated by O3 (1.21, SD: 1.27). SO2 had the highest mean Air Quality Index (AQI) value (mean: 84, SD: 36), whereas O3 showed the lowest (mean: 42, SD: 13). PM2.5 showed a significant positive association with stroke incidence (IRR: 1.003, 95% CI: 1.001-1.005, P < 0.001), corresponding to a 0.3% increase in stroke incidence per unit rise in PM2.5-related AQI. No statistically significant associations were observed for the other air pollutants.
Conclusion: Elevated PM2.5 levels were associated with increased stroke incidence, while other air pollutants showed no significant correlations. These findings underscore the importance of effective management of particulate matter sources and the strengthening of air quality monitoring systems to mitigate stroke risk.
Type of Study: Original Article |
Subject:
Environmental Health, Sciences, and Engineering
Received: 2025/12/29 | Accepted: 2026/03/19
Received: 2025/12/29 | Accepted: 2026/03/19
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