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Volume 10, Issue 2 (5-2024)
jhehp 2024, 10(2): 79-82 |
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Heidari A, Ghodrati S, Mobaien A, Fazaeli A. Pulmonary Infection of Lophomonas blattarum as a Co-infection with COVID-19 in Patients with Severe Pneumonia. jhehp 2024; 10 (2) :79-82
URL: http://jhehp.zums.ac.ir/article-1-632-en.html
URL: http://jhehp.zums.ac.ir/article-1-632-en.html
1- Social Determinants of Health Research Center, Health and Metabolic Diseases Research Institute, Zanjan University of Medical Sciences, Zanjan, Iran; Department of Medical Parasitology & Mycology, Medical School, Zanjan University of Medical Sciences, Zanjan, Iran.
2- Department of Internal Medicine, Medical School, Zanjan University of Medical Sciences, Zanjan, Iran.
3- Department of Infectious Diseases, Medical School, Zanjan University of Medical Sciences, Zanjan, Iran.
4- Department of Medical Parasitology & Mycology, Medical School, Zanjan University of Medical Sciences, Zanjan, Iran.
2- Department of Internal Medicine, Medical School, Zanjan University of Medical Sciences, Zanjan, Iran.
3- Department of Infectious Diseases, Medical School, Zanjan University of Medical Sciences, Zanjan, Iran.
4- Department of Medical Parasitology & Mycology, Medical School, Zanjan University of Medical Sciences, Zanjan, Iran.
Abstract: (348 Views)
Background: Lophomonas blattarum is a newly reported opportunistic protozoan parasite that may cause pulmonary infections. Co-morbidity of this parasite and pulmonary viral infections, such as COVID-19 may exacerbate their pathological effects. This study aimed to evaluate the prevalence of L. blattarum infection in patients with COVID-19 infection.
Methods: In this study, mini bronchoalveolar lavage (mini-BAL) samples were taken from 93 patients with acute pneumonia due to COVID-19 infection in 2021. The samples were subjected to microscopic examination for the presence of L. blattarum, following smear preparation and staining with two specific methods of Giemsa and Papanicolao.
Results: The patients included 49 males and 44 females with a mean age of 68.8 ± 14.8 years. Of the specimens studied after staining, only one specimen (1.08%) was positive for L. blattarum. It was found in a patient with diabetic underlying disease.
Conclusion: It was concluded that the infection of L. blattarum in patients with severe COVID-19 pneumonia was low. However, the presence of this parasite in this group of patients should not be neglected. This is the first report of pulmonary infection with this protozoan parasite in Zanjan Province.
Methods: In this study, mini bronchoalveolar lavage (mini-BAL) samples were taken from 93 patients with acute pneumonia due to COVID-19 infection in 2021. The samples were subjected to microscopic examination for the presence of L. blattarum, following smear preparation and staining with two specific methods of Giemsa and Papanicolao.
Results: The patients included 49 males and 44 females with a mean age of 68.8 ± 14.8 years. Of the specimens studied after staining, only one specimen (1.08%) was positive for L. blattarum. It was found in a patient with diabetic underlying disease.
Conclusion: It was concluded that the infection of L. blattarum in patients with severe COVID-19 pneumonia was low. However, the presence of this parasite in this group of patients should not be neglected. This is the first report of pulmonary infection with this protozoan parasite in Zanjan Province.
Type of Study: Original Article |
Subject:
Public Health
Received: 2024/03/14 | Accepted: 2024/04/20 | Published: 2024/05/4
Received: 2024/03/14 | Accepted: 2024/04/20 | Published: 2024/05/4
References
1. Agrawal, D., Jaiswal, P., & Goyanka, B. (2020). Diabetes and covid-19: A review. International Journal of Research in Pharmaceutical Sciences, 376-379. [Crossref] [Google Scholar]
2. Alam-Eldin, Y. H., & Abdulaziz, A. M. (2015). Identification criteria of the rare multi-flagellate Lophomonas blattarum: comparison of different staining techniques. Parasitology Research, 114, 3309-3314. [Crossref] [Google Scholar]
3. Berenji, F., Parian, M., Fata, A., Bakhshaee, M., & Fattahi, F. (2016). First case report of sinusitis with Lophomonas blattarum from Iran. Case Reports in Infectious Diseases, 1-2. [Crossref] [Google Scholar]
4. Berenji, F., Fata, A., Vakili, V., Sayedi, S. J., Abdollahi, B., Imanfar, H., ... & Khorasani, S. R. (2016b). Unexpected high rate of Lophomonas blattarum in resistant upper and lower respiratory infection. Health Sciences, 5(9), 74-80. [Google Scholar]
5. Ding, Q., & Shen, K. (2021). Pulmonary infection with Lophomonas blattarum. The Indian Journal of Pediatrics, 88, 23-27. [Crossref] [Google Scholar]
6. Fakhar, M., Nakhaei, M., Sharifpour, A., Safanavaei, S., Abedi, S., Tabaripour, R., ... & Banimostafavi, E. S. (2021). Morphological and molecular identification of emerged Lophomonas blattarum infection in Mazandaran Province, northern Iran: first registry-based study. Acta Parasitologica, 66(4), 1510-1516. [Crossref] [Google Scholar]
7. Gebrecherkos, T., Gessesse, Z., Kebede, Y., Gebreegzabher, A., Tasew, G., Abdulkader, M., ... & Wolday, D. (2021). Effect of co-infection with parasites on severity of COVID-19. MedRxiv, 1-15. [Crossref] [Google Scholar]
8. Ghafarian, N., Bakhtiari, E., Berenji, F., Nakhaei, M., Nakhaei, B., Jamali-Behnam, F., & Sayedi, J. (2018). The study of Lophomonas blattarum infection in children with respiratory symptoms: a descriptive clinical study in north east of Iran. International Journal of Pediatrics, 6(6), 7797-7802. [Google Scholar]
9. Gharebaghi, R., Heidary, F., Moradi, M., & Parvizi, M. (2020). Metronidazole; a potential novel addition to the COVID-19 treatment regimen. Archives of Academic Emergency Medicine, 8(1), e40. [Crossref] [Google Scholar]
10. Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., ... & Cao, B. (2020). Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The Lancet, 395(10223), 497-506. [Crossref] [Google Scholar]
11. Keighobadi, M., Nakhaei, M., Sharifpour, A., Khasseh, A. A., Safanavaei, S., Tabaripour, R., ... & Fakhar, M. (2021). A bibliometric analysis of global research on Lophomonas Spp. in Scopus (1933-2019). Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders), 21(2), 230-237. [Crossref] [Google Scholar]
12. Li, R., & Gao, Z. C. (2016). Lophomonas blattarum infection or just the movement of ciliated epithelial cells?. Chinese Medical Journal, 129(06), 739-742. [Crossref] [Google Scholar]
13. Martinez-Girón, R., & Cornelis van Woerden, H. (2013). Lophomonas blattarum and bronchopulmonary disease. Journal of Medical Microbiology, 62(11), 1641-1648. [Crossref] [Google Scholar]
14. Mirzazadeh, F., Berenji, F., Amini, M., Salehi, M., Shamsian, A., Fata, A., ... & Ghofraniha, L. (2017). Lophomonas blattarum in asthmatic patients and control group. Journal of Research in Medical and Dental Science, 5(5), 1-5. [Google Scholar]
15. Nakhaei, M., Fakhar, M., Sharifpour, A., Banimostafavi, E. S., Zakariaei, Z., Mehravaran, H., ... & Soleimani, M. (2022). First co-morbidity of Lophomonas blattarum and COVID-19 infections: confirmed using molecular approach. Acta Parasitologica, 1-4. [Crossref] [Google Scholar]
16. Sharifpour, A., Zakariaei, Z., Fakhar, M., Banimostafavi, E. S., Nakhaei, M., & Soleymani, M. (2021). Post‐COVID‐19 co‐morbidity of emerged Lophomonas infection and invasive pulmonary aspergillosis: first case report. Clinical Case Reports, 9(9), e04822. [Crossref] [Google Scholar]
17. Singhal, T. (2020). A review of coronavirus disease-2019 (COVID-19). The Indian Journal of Pediatrics, 87(4), 281-286. [Crossref] [Google Scholar]
18. Song, F., Shi, N., Shan, F., Zhang, Z., Shen, J., Lu, H., ... & Shi, Y. (2020). Emerging 2019 novel coronavirus (2019-nCoV) pneumonia. Radiology, 295(1), 210-217. [Crossref] [Google Scholar]
19. Wang, Y., Tang, Z., Ji, S., Zhang, Z., Chen, J., Cheng, Z., ... & Li, L. (2006). Pulmonary Lophomonas blattarum infection in patients with kidney allograft transplantation. Transplant International, 19(12), 1006-1013. [Crossref] [Google Scholar]
20. Xue, J., Li, Y. L., Yu, X. M., Li, D. K., Liu, M. F., Qiu, J. F., & Xue, J. J. (2014). Bronchopulmonary infection of Lophomonas blattarum: a case and literature review. The Korean Journal of Parasitology, 52(5), 521-525. [Crossref] [Google Scholar]
21. Zhou, F., Yu, T., Du, R., Fan, G., Liu, Y., Liu, Z., ... & Cao, B. (2020). Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. The Lancet, 395(10229), 1054-1062. [Crossref] [Google Scholar]
22. Zhu, X., Ge, Y., Wu, T., Zhao, K., Chen, Y., Wu, B., ... & Cui, L. (2020). Co-infection with respiratory pathogens among COVID-2019 cases. Virus Research, 285, 198005. [Crossref] [Google Scholar]
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