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Volume 8, Issue 2 (6-2022)
jhehp 2022, 8(2): 69-76 |
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Dizaji R. Real-Life Toxicants as an Emerging Challenge in the Rehabilitation of COVID-19 Survivors. jhehp 2022; 8 (2) :69-76
URL: http://jhehp.zums.ac.ir/article-1-525-en.html
URL: http://jhehp.zums.ac.ir/article-1-525-en.html
Department of Food Safety and Hygiene, School of Public Health, Zanjan University of Medical Sciences, Zanjan, Iran.
Abstract: (4010 Views)
Awareness of COVID-19 infection, as a public crisis, makes an emergency condition for survivors. Regarding the importance of early rehabilitation, we should pay particular attention to the potential risk of real-life toxicants in COVID-19 survivors. The adverse effects underlying COVID-19 infection lead to persistent sequelae in survivors. In addition, complete rehabilitation is challenging in seriously-ill patients due to cytokine storm severity, inflammation, oxidative stress, and cell death contributing to multi-organ damage. Different foods, environmental/occupational pollutants, and unhealthy lifestyles are real-life examples of toxicants that can pose redox imbalance and oxidative damage to the biological system. The key concept is that survived patients with persistent tissue damage, low-grade inflammation, oxidative stress, and fibrosis are susceptible to real-life toxic stressors, which have the potential for oxidative stress. Moreover, fibrosis are susceptible to toxic stressors, which can induce harmful effects by promoting oxidative stress and pro-inflammatory components. This paper attempted to elucidate a vital toxicological concept in which the existing sequelae of COVID-19 survivors increase the potential risk of real-life toxicants and to propose a practical strategic approach to reduce toxicant exposure.
Abbreviation: Lipid radical (L•), Lipid peroxyl radical (LOO•), Lipid alkoxyl radical (LO•), particulate matter (PM), reactive oxygen species (ROS), ultra-fine particle (UFP).
Abbreviation: Lipid radical (L•), Lipid peroxyl radical (LOO•), Lipid alkoxyl radical (LO•), particulate matter (PM), reactive oxygen species (ROS), ultra-fine particle (UFP).
Type of Study: Review Article |
Subject:
Public Health
Received: 2022/03/29 | Accepted: 2022/05/28 | Published: 2022/06/18
Received: 2022/03/29 | Accepted: 2022/05/28 | Published: 2022/06/18
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