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Volume 5, Issue 4 (12-2019)
jhehp 2019, 5(4): 183-187 |
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Moghadami M, Sheybani M, Reziaean Zadeh A, Rakhshani T. Evaluation of the Prevalence of Thalassemia and Sickle Hemoglobin in Marriage Applicants Referring to the Genetic Disease Counseling Center in Kazeroun, Iran during 2014-2018. jhehp 2019; 5 (4) :183-187
URL: http://jhehp.zums.ac.ir/article-1-224-en.html
URL: http://jhehp.zums.ac.ir/article-1-224-en.html
1- Non Communicable Disease Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
2- Community Education, School of Public Health, Shiraz University of Medical Sciences, Shiraz, Iran.
3- Departemant of Epidemiology, Faculty of Public Health, Shiraz Univercity of Medical Science,Shiraz,Iran.
4- Nutrition Research Center , Department of Public Health, School of Public Health, Shiraz University of Medical Sciences, Shiraz, Iran.
2- Community Education, School of Public Health, Shiraz University of Medical Sciences, Shiraz, Iran.
3- Departemant of Epidemiology, Faculty of Public Health, Shiraz Univercity of Medical Science,Shiraz,Iran.
4- Nutrition Research Center , Department of Public Health, School of Public Health, Shiraz University of Medical Sciences, Shiraz, Iran.
Abstract: (9269 Views)
Background: The present study aimed to determine the prevalence of thalassemia minor and sickle hemoglobin in marriage applicants referring to the Genetic Diseases Counseling Center of Kazeroun Health Center over 2014-2018.
Methods: This cross-sectional study was conducted in Kazeroun, Iran. The statistical population included all couples referring to the marriage counseling centers in Kazeroun for pre-marriage tests during 2014-2018. In this study, the registration data associated with the health records of the couples seeking marriage counseling were used.
Results: Over the years under scrutiny, 31114 applicants (15557 couples) referred to the health counseling center for marriage tests under the supervision of the health network. Among the marriage applicants, the highest prevalence of beta-thalassemia, alpha-thalassemia, anemia, sickle cell hemoglobin, and hemoglobinopathy was reported in 2014 (0.07), 2018 (0.15), 2014 (0.66), 2018 (0.9), and 2014 (0.05), respectively.
Conclusion: The results of the present study showed that the prevalence of thalassemia and sickle cell anemia in Kazeroun over the study years was similar to that in other parts of Iran over the same years.
Methods: This cross-sectional study was conducted in Kazeroun, Iran. The statistical population included all couples referring to the marriage counseling centers in Kazeroun for pre-marriage tests during 2014-2018. In this study, the registration data associated with the health records of the couples seeking marriage counseling were used.
Results: Over the years under scrutiny, 31114 applicants (15557 couples) referred to the health counseling center for marriage tests under the supervision of the health network. Among the marriage applicants, the highest prevalence of beta-thalassemia, alpha-thalassemia, anemia, sickle cell hemoglobin, and hemoglobinopathy was reported in 2014 (0.07), 2018 (0.15), 2014 (0.66), 2018 (0.9), and 2014 (0.05), respectively.
Conclusion: The results of the present study showed that the prevalence of thalassemia and sickle cell anemia in Kazeroun over the study years was similar to that in other parts of Iran over the same years.
Type of Study: Original Article |
Subject:
Public Health
Received: 2019/08/14 | Accepted: 2019/10/23 | Published: 2019/12/21
Received: 2019/08/14 | Accepted: 2019/10/23 | Published: 2019/12/21
References
1. Hojjati MT, Einollahi N, Nabatchian F,Pourfathollah AA, Mahdavi MR. Allelespecific Oligonucleotide Polymerase Chainreaction for the Determination of Rh C/c andRh E/e antigens in thalassaemic Patients. Blood Transfus. 2011; 9(3): 301-5.
2. Soteh H, Akhavan Niaki H, Kowsarian M, Aliasgharian A, Banihashemi A. Frequency of Beta-globin Gene Mutations in Beta-thalassemia Patients from East of Mazandaran. J Mazand Univ Med Sci. 2008; 18(67): 17-25.
3. Ghotbi N, Tsukatani T. Evaluation of the National Health Policy of thalassaemia screening in the Islamic Republic of Iran. East Mediterr Health J. 2005; 11(3): 308-18.
4. Olivieri NF. Medical progress: The β-Thalassemias. N England J Med. 1999; 341: 99-109. [Crossref]
5. Finotti A, Breda L, Lederer CW, Bianchi N, Zuccato C, Kleanthous M, et al. Recent trends in the gene therapy of β-thalassemia. J Blood Med. 2015; 19(6): 69-85. [Crossref]
6. Rachmilewitz EA, Giardina PJ. How I treat thalassemia. Blood. 2011; 118(13): 3479-88. [Crossref]
7. Bordbar E, Taghipour M, Zucconi BE. Reliability of Different RBC Indices and Formulas in Discriminating between β-thalassemia Minor and Other Microcytic Hypochromic Cases. Mediterr J Hematol Infect Dis. 2015; 7(1): e2015022. [Crossref]
8. Rahim F, Abromand M. Spectrum of ß –thalassemia mutations in various ethnic regions of Iran. Pak J Med Sci. 2008; 24(3): 410-5.
9. Miri M, Tabrizi NM, Hadipour DM, Sadeghian VF, Ahmadvand A, Yousefi D, et al. Thalassemia in Iran in Last Twenty Years: the Carrier Rates and the Births Trend. Iran J Blood Cancer. 2013; 6(1): 11-8.
10. Valizadeh F, Mousavi A, Hashemi-Soteh MB. Prevalence of Hemoglobinopathies in Premarriage Individuals Referred to Babolsar, Iran (2006-09). J Gorgan Uni Med Sci. 2012; 14(1): 106-12.
11. Zandian Kh, Keikhaie B, Pedram M, Kianpoor Ghahfarokhi F. Prenatal Diagnosis and Frequency Determination of Alpha and Beta, Thalassemia, S, D, C, and H Hemoglobinopathies; Globin, Mutational Genes, Aanalysis among Voluntary Couples from Ahvaz. Iran J Blood Cancer. 2009; 1(3): 95-8.
12. Tamaddoni A, Hadavi V, Nejad NH, Khosh Ain A, Siami R, Aghai Meibodi J, et al.Alpha-Thalassemia Mutation Analyses in Mazandaran Province, North Iran. Hemoglobin. 2009; 33(2): 115-23. [Crossref]
13. Pooladi N, Hosseinpour Feizi MA, Haghi M, Azarfam P, Hosseinpour Feizi AA. Analysis of Beta Thalassemia Mutations Using the Single Strand Conformation Polymorphism (SSCP) Technique. Sci J Kurdistan Univ Med Sci. 2010; 15(3): 13-9.
14. Nezhad FH, Nezhad KH, Choghakabodi PM, Keikhaei B. Prevalence and Genetic Analysis of α-and β-Thalassemia and Sickle Cell Anemia in Southwest Iran. J Epidemiol Glob Health. 2018; 8(3): 189-95. [Crossref]
15. Aziz M, Anwar M. Prevalence of Beta Thalassemia Trait in Quetta City, Cross Section Study. JUMDC. 2015; 6(4): 21-6.
16. Sharma A, Vageriya V. Prevalence of Thalassemia in Reproductive Age Group Females in Central Gujarat-Literature Review. Int J Nurs Educ. 2017; 9(2): 71-4. [Crossref]
17. Lai K, Huang G, Su L, He Y. The Prevalence of Thalassemia in Mainland China: Evidence from Epidemiological Surveys. Sci Rep. 2017; 7(1): 920. [Crossref]
18. Ahmed MM, Salaria SM, Qamar S, SoazM A, BukhariM H, QureshiA H. Incideneof β-Thalassemia Carriers in Muzaffarabad, Azad Kashmir. Ann Punjab Med College. 2016; 10(1): 11-9.
19. Lau YL, Chan LC, Chan YY, Ha SY, Yeung CY, Waye JS, Chui DH. Prevalence and Genotypes of Alpha-and Beta-Thalassaemia Carriers in Hong Kong-Implications for Population Screening. N Engl J Med. 1997; 336: 1298-301. [Crossref]
20. Valizadeh F, Deylami A. Prevalence of Mutations of Alpha Globin Gene in Suspected Alpha Carrier Couples, Babolsar, 2006-2011. J Mazandaran Univ Med Sci. 2014; 23(109): 17-25.
21. Zandi Kh, Pedram M. Distribution of Alphathalassemia Mutations in Khuzestan Province: Genetics of the Third Millennium. Hemoglobin. 2007; 7(15): 33-42.
22. Neishabury ML, Abbasi Moheb L, Najmabadi H. Alpha-Thalassemia Deletion Analysis in Iran. Arch Iran Med. 2001; 4(4): 160-4.
23. El Kalla S, Baysal E. Alpha-Thalassemia in the United Arab Emirates. Acta Haematol. 1998; 100(1): 49-53. [Crossref]
24. Borges E, Wenning MR, Kimura EM, Gervásio SA, Sonati MF,Costa FF. High Prevalence of Alpha-Thalassemia among Individuals with and Hypochromia without Anemia. Braz J Med Biol Res. 2001; 34(6):
25. Adekile AD, Gu LH, Baysal E, Haider MZ, Al Fuzae L, Aboobacker KC, et al. Molecular Characterization of Alphathalassemia Determinants, Beta-Thalassemia Alleles and Beta S Haplotypes among Kuwaiti Arabs. Acta Haematol. 1994; 92(4): 176-81. [Crossref]
26. White JM, Byrne M, Richards R, Buchanan TKatsoulis E, Weerasingh K. Red Cell Geneticabnormalities in Peninsular Arabsalphathalassemia. J Med Genet. 1986; 23(3): 245-51. [Crossref]
27. Fowkes FJ, Allen SJ, Allen A, Alpers MP, Weatherall DJ, Day KP. Increased Microerythrocyte Count Inhomozygous Alpha(+)- Thalassaemia Contributes Toprotection against Severe Malarial Anaemia. PLoS Med.2008; 5(3): e56.
28. Canatan D. Thalassemias and Hemoglobinopathies in Turkey. Hemoglobin. 2014; 38(5): 305-7. [Crossref]
29. El Ariss AB, Younes M, Matar J, Berjaoui Z. Prevalence of Sickle Cell Trait in the Southern Suburb of Beirut, Lebanon. Mediterr J Hematol Infect Dis. 2016; 8(1): e2016015. [Crossref]
30. Hemminki K, Li X, Försti A, Sundquist J, Sundquist K. Thalassemia and Sickle Cell Anemia in Swedish Immigrants: Genetic Diseases have become Global. Sage Open Med. 2015; 3: 2050312115613097. [Crossref]
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