en Environmental Health, Sciences, and Engineering Environmental Health, Sciences, and Engineering پژوهشي Original Article <div style="text-align: justify;"><span style="font-family:Times New Roman;"><span style="font-size:14px;"><strong>Background:</strong> Heavy metal toxicity at low levels damages the function of the brain, lungs, kidney, liver, blood composition, and other important organs. Long-term exposure leads to gradual disease progression in multiple sclerosis, Parkinson&rsquo;s disease, Alzheimer&rsquo;s disease, muscular dystrophy, and cancer.<br> <strong>Methods:</strong> In total, 100 crustacean samples (50 crabs and 50 prawns) were analyzed in terms of nickel, zinc, chromium, and copper residues using an atomic absorption spectrophotometer and compared to Egyptian standard limits.<br> <strong>Results:</strong> The concentrations of nickel, zinc, chromium, and copper in the crab samples were 0.292 &plusmn; 0.02, 20.688 &plusmn; 3.06, 1.158 &plusmn; 0.01, and 22.304 &plusmn; 4.04 &micro;g/g of wet weight, respectively. The values in the prawn samples were 0.373 &plusmn; 0.01, 16.204 &plusmn; 2.01, 0.844 &plusmn; 0.01, and 18.524 &plusmn; 1.03 &micro;g/g of wet weight, respectively.<br> <strong>Conclusion:</strong> Our findings could lay the groundwork for monitoring the heavy metal contamination of marine organisms. The estimated daily detection intake of nickel, zinc, chromium, and copper was below the reported PTDI of each element. In addition, the THQ and HI values of the heavy metals were below 1.00 in the crab and shrimp samples, suggesting no significant risks to the community health due to the consumption of the crab and shrimp samples.</span></span></div> Heavy metals, Crab, Prawn, Risk assessment, 6 14 http://jhehp.zums.ac.ir/browse.php?a_code=A-10-298-2&slc_lang=en&sid=1 Hanan A. Zaher hananzaher787@gmail.com 100319475328460011134 100319475328460011134 No Department of Food Hygiene and Control, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt. Azza H. Mohamed azza@ufl.edu 100319475328460011135 100319475328460011135 No Department of Agricultural Chemistry , Faculty of Agriculture, Mansoura University, Egypt. Sahar E. Hamed s.hamed@du.edu.eg 100319475328460011136 100319475328460011136 No Department of Chemistry , Faculty of Agriculture, Damietta University, Damietta, Egypt. Ayman El-Khateeb aymanco@mans.edu.eg 100319475328460011137 100319475328460011137 Yes Department of Agricultural Chemistry , Faculty of Agriculture, Mansoura University, Egypt.