en Public Health Public Health پژوهشي Original Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:times new roman;"><strong>Background:</strong> Tuberculosis is a major cause of morbidity and mortality in Africa, especially Ghana. Despite the current treatments for tuberculosis, positive treatment outcomes are not attainable due to the differences in the socio-economic and bio-psychological status of the patients. The present study aimed to assess the influential factors in the treatment outcomes of tuberculosis.<br> <strong>Methods: </strong>This qualitative study was conducted to determine the influential factors in the treatment outcomes of tuberculosis in terms of the patients, community, and healthcare providers. Data collection and management were performed using version 11 of the NVivo software. Sample population included 10 patients, five healthcare providers, and five community members (treatment supporters). Data analysis was carried out using framework analysis, where the emerging themes were identified and discussed in relation with literature.<br> <strong>Results:</strong> The results revealed that wrong/negative perceptions about TB, social stigma, and the use of alternative treatment methods could result in unsuccessful treatment outcomes.<br> <strong>Conclusion:</strong> The study recommends that community awareness of TB and the search and implementation of policies toward improving TB treatment outcome should be pursued.</span></span></div> Tuberculosis, Treatment outcomes, HIV comorbidity, Communities. 99 105 http://jhehp.zums.ac.ir/browse.php?a_code=A-10-185-1&slc_lang=en&sid=1 Eunice Twumwaa Tagoe etadwubi@gmail.com 10031947532846009589 10031947532846009589 No Department of Health Policy, Planning and Management, School of Public Health, University of Ghana. Pascal Agbadi pascalagbadi@gmail.com 10031947532846009590 10031947532846009590 Yes Department of Health Policy, Planning and Management, School of Public Health, University of Ghana. Augustine Adomah-Afari augustineafari@yahoo.co.uk 10031947532846009591 10031947532846009591 No Department of Health Policy, Planning and Management, School of Public Health, University of Ghana.